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The Hepatoprotective Action of Ellagotannins

PubMed Abstract PMID: 9854636
This abstract also posted in the files section of the K9Kitchen discussion group.

Monica's Comments
This study found that Altan (found in ellagotannins) exhibited liver-protective properties in small doses, about one-tenth the amount of compariable flavonoid-based drugs. It limits bile disorders, stabilizes membranes and helps the body's ability to protect itself from oxidants.

The Abstract
The hepatoprotective properties of altan (obtained on the basis of ellagotannines from the cones of black alder Alnus glutinosa) are studied on the model of acute damage to the liver with tetrachloromethane. It is found that altan exhibits the hepatoprotective activity even in a dose of 1 mg/kg which is tenfold smaller compared to the dose of traditional flavonoid-based drugs. Altan limits choleopoiesis disorder, has an antiinflammatory and membrane stabilizing effect, and recovers physiological antioxidant system.

Study Authors
Buniatian ND, Chikitkina VV, Iakovleva LV
Ukrainian Pharmaceutical Academy, Khar'kov, Ukraine

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